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|Issue Date: ||16-Mar-2018|
|Authors: ||Sciuto, Emanuele Luigi|
|Title: ||Development of Innovative Technologies for DNA Extraction and Detection|
|Abstract: ||The Ph.D. project has been focused on the development of fast, multiplex, innovative and easy-to-use technological platforms for DNA analysis (from extraction to detection), implemented into portable and miniaturized devices. These types of technologies are called Point-of-Care (PoC) and could create the conditions for a more efficient clinical analysis, introducing a series of advantages:
Fast and cheap procedures for biological samples preparation and analysis
Identification and analysis of different DNA mutations (complex phenotypes and drug-resistance related)
Disease-specific and therapy-specific pattern definition
My research activity has been divided into three main parts, which will be described in the subsequent chapters:
1. Development and characterization of a miniaturized platform for DNA extraction.
2. Development and characterization of miniaturized systems for DNA detection with both optical transduction methods (via RT-PCR) and electrical methods (electrochemical detection).
3. Development of molecular methods for the detection of environmental analytes.|
|Appears in Collections:||Area 02 - Scienze fisiche|
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